Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559784 | 0.83 | PLA2G2D (0.54) | MLYCDKDM4E | |
| SCHEMBL8643468 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL3903297 | 0.79 | NOTUM (0.59) | NOTUMKDM4EALDH1A1PDK2GLA | |
| SCHEMBL13220716 | 0.77 | CA1 (0.53) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL3903628 | 0.77 | NOTUM (0.51) | NOTUMKDM4EALDH1A1PDK2GLA | |
| SCHEMBL12263286 | 0.76 | CA1 (0.49) | NOTUMKDM4EALDH1A1GLAGAA | |
| SCHEMBL3908210 | 0.76 | NOTUM (0.63) | NOTUMKDM4EALDH1A1PDK2GLA | |
| SCHEMBL29820330 | 0.75 | CA1 (0.47) | NOTUMKDM4EALDH1A1GLAGAA | |
| SCHEMBL26817457 | 0.75 | CA1 (0.47) | NOTUMKDM4EALDH1A1GLAGAA | |
| SCHEMBL2159198 | 0.75 | ACE2 (0.54) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747541-A | Substituted benzoylguanidines, a process for their preparation, their use as medicament of diagnostic agent, and medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | disclosed |