Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556404 | 0.89 | MEN1 (0.69) | LMNASMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL8558009 | 0.88 | CA1 (0.69) | LMNAMEN1KMT2ACA1CA2 | |
| SCHEMBL8559166 | 0.88 | LMNA (0.67) | LMNASMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL8554326 | 0.84 | LMNA (0.58) | LMNASMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL4023715 | 0.84 | CA1 (0.67) | MEN1KMT2ACA1CA2CA12 | |
| SCHEMBL8558635 | 0.84 | TAAR1 (0.70) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL8558637 | 0.83 | LMNA (0.58) | LMNAMEN1KMT2ACA1CA2 | |
| SCHEMBL8553751 | 0.82 | CA1 (0.65) | LMNASMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL6392255 | 0.80 | LTA4H (0.61) | LMNAKMT2ACA1CA2LTA4H | |
| SCHEMBL28000837 | 0.80 | KMT2A (0.64) | LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5498717-A | CHEMICAL INTERMEDIATES FOR PRODUCING ANTITUMOR POTENTIATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5446164-A | Regioselective cyclization of phenethylamide derivative in presence of phosphoric acid halide, reducing formed compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0617022-A1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |