Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557311 | 0.88 | ADORA1 (0.38) | NR1H2BRD4CREBBPHDAC6PRMT5 | |
| SCHEMBL8556840 | 0.87 | ESR2 (0.40) | NR1H2BRD4CREBBPHDAC6PRMT5 | |
| SCHEMBL8558319 | 0.86 | ITGB3 (0.48) | NR1H2BRD4CREBBPHDAC6PRMT5 | |
| SCHEMBL8558878 | 0.83 | TPSAB1 (0.46) | NR1H2BRD4CREBBPHDAC6PRMT5 | |
| SCHEMBL8556021 | 0.81 | F2 (0.41) | NR1H2BRD4CREBBPHDAC6PRMT5 | |
| SCHEMBL8557314 | 0.76 | ITGB3 (0.51) | HDAC6PRMT5WDR77MAPTITGB3 | |
| SCHEMBL8556843 | 0.75 | ITGB3 (0.48) | NR1H2HDAC6PRMT5WDR77ESR2 | |
| SCHEMBL8553064 | 0.73 | ITGB3 (0.62) | HDAC6PRMT5WDR77ITGB3ITGA2B | |
| SCHEMBL8558884 | 0.72 | ITGB3 (0.53) | NR1H2HDAC6PRMT5WDR77ESR2 | |
| SCHEMBL7834582 | 0.72 | ITGB3 (0.47) | NR1H2BRD4CREBBPHDAC6ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |