⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641238 | 0.84 | — | — | |
| SCHEMBL8560163 | 0.84 | MEN1 (0.31) | — | |
| SCHEMBL6992694 | 0.83 | — | — | |
| SCHEMBL9641316 | 0.80 | LRRK2 (0.31) | — | |
| SCHEMBL8556082 | 0.79 | CCR4 (0.41) | — | |
| SCHEMBL7851051 | 0.76 | CA12 (0.32) | — | |
| SCHEMBL9641789 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL8825998 | 0.75 | CCR4 (0.32) | — | |
| SCHEMBL9642168 | 0.75 | ADORA3 (0.34) | — | |
| SCHEMBL9642706 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0537611-A1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5177206-A | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-01-05 | — | — | US | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |