Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | S100A4 | P26447 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912390 | 0.89 | S100A4 (0.59) | CYP3A4S100A4TSHRTDP1CTSB | |
| SCHEMBL29674860 | 0.88 | CYP3A4 (0.70) | CYP3A4S100A4TSHRTDP1CTSB | |
| SCHEMBL2285808 | 0.88 | CYP3A4 (0.70) | CYP3A4S100A4TSHRTDP1CTSB | |
| SCHEMBL2829878 | 0.80 | S100A4 (0.64) | CYP3A4S100A4TSHRTDP1CTSB | |
| SCHEMBL19033408 | 0.77 | CYP3A4 (0.57) | CYP3A4S100A4TSHRTDP1ALDH1A1 | |
| SCHEMBL7915412 | 0.77 | S100A4 (0.80) | CYP3A4S100A4TSHRTDP1CTSB | |
| SCHEMBL7905236 | 0.74 | CYP3A4 (0.53) | CYP3A4S100A4TSHRTDP1ALDH1A1 | |
| SCHEMBL28511 | 0.74 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29352635 | 0.74 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29450703 | 0.73 | CYP3A4 (1.00) | CYP3A4S100A4TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |