Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225420 | 0.83 | NPC1 (0.40) | NPC1RAB9APDE10AALDH1A1TSHR | |
| SCHEMBL6552357 | 0.79 | HPGD (0.40) | NPC1RAB9APDE10AALDH1A1TSHR | |
| SCHEMBL10519274 | 0.75 | ALDH1A1 (0.40) | NPC1RAB9APDE10AALDH1A1TSHR | |
| SCHEMBL8355273 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL3190914 | 0.74 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL8881888 | 0.73 | KDM4E (0.46) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL7840633 | 0.71 | JAK2 (0.45) | NPC1RAB9APDE10AALDH1A1MEN1 | |
| SCHEMBL10660778 | 0.71 | HPGD (0.40) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL8113305 | 0.71 | HTR6 (0.36) | ALDH1A1LMNAUSP2HTR6 | |
| SCHEMBL8559896 | 0.71 | MAP4K4 (0.33) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630377-A1 | TRIAZOLOPYRIMIDINESULFONAMIDES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1994-12-28 | — | — | EP | claimed |
| WO-1993016079-A1 | TRIAZOLOPYRIMIDINESULFONAMIDES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1993-08-19 | — | — | WO | claimed |
| EP-0142811-A2 | Method of preparing 1,2,4-triazolo [1,5-a] - pyrimidine-2-sulfonyl chlorides | THE DOW CHEMICAL COMPANY (US) | 1985-05-29 | — | — | EP | claimed |
| JP-60172984-A | — | — | None | — | — | JP | disclosed |
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| US-5602075-A | N-aryl[1,2,4]triazolo[1,5-a]pyrazine-2-sulfonamide herbicides | DOWELANCO (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0630377-A1 | TRIAZOLOPYRIMIDINESULFONAMIDES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1994-12-28 | — | — | EP | disclosed |
| EP-0340828-B1 | 5-Fluoromethyl-1,2,4-triazolo(1,5-a)-pyrimidine-2-sulfonamides, process for their preparation and compositions for their use as herbicides | DOWELANCO (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1993016079-A1 | TRIAZOLOPYRIMIDINESULFONAMIDES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1993-08-19 | — | — | WO | disclosed |
| EP-0537611-A1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5177206-A | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-01-05 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4734123-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0142811-A3 | Method of preparing 1,2,4-triazolo [1,5-a] - pyrimidine-2-sulfonyl chlorides | THE DOW CHEMICAL COMPANY (US) | 1986-03-12 | — | — | EP | disclosed |
| EP-0142811-A3 | Method of preparing 1,2,4-triazolo [1,5-a] - pyrimidine-2-sulfonyl chlorides | THE DOW CHEMICAL COMPANY (US) | 1986-03-12 | — | — | EP | disclosed |
| JP-S60172984-A | MANUFACTURE OF 1,2,4-TRIAZOLO(1,5-A)- PYRIMIDINE-2-SULFONYLCHLORIDE | DOW CHEMICAL CO | 1985-09-06 | — | — | JP | disclosed |
| EP-0142811-A2 | Method of preparing 1,2,4-triazolo [1,5-a] - pyrimidine-2-sulfonyl chlorides | THE DOW CHEMICAL COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0142811-A2 | Method of preparing 1,2,4-triazolo [1,5-a] - pyrimidine-2-sulfonyl chlorides | THE DOW CHEMICAL COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0142811-A2 | Method of preparing 1,2,4-triazolo [1,5-a] - pyrimidine-2-sulfonyl chlorides | THE DOW CHEMICAL COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0142152-A2 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |