SCHEMBL8558505

SCHEMBL8558505

CCC(C(=O)OC1CCCC1)N1C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)C1(C)C

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 10/20 0.51
PGR P06401 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559864 0.85 AR (0.61) ARPGR
SCHEMBL4192693 0.82 AR (0.61) ARPGR
SCHEMBL4195979 0.79 AR (0.67) ARPGR
SCHEMBL4032336 0.76 AR (0.65) ARPGR
Acetic Acid SCHEMBL8561856 0.75 AR (0.55) ARPGR
SCHEMBL24684821 0.74 AR (0.63) ARPGR
SCHEMBL4196099 0.73 AR (0.66) ARPGR
SCHEMBL4027208 0.73 AR (0.74) ARPGR
SCHEMBL4028572 0.72 AR (0.86) ARPGR
SCHEMBL3997254 0.72 AR (0.65) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35956-E Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1998-11-10 US disclosed
US-5627201-A Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1997-05-06 US disclosed
US-5411981-A Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1995-05-02 US disclosed