SCHEMBL8559864

SCHEMBL8559864

CCC(C(=O)O)N1C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)C1(C)C

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 10/20 0.61
PGR P06401 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8558505 0.85 AR (0.51) ARPGR
SCHEMBL4032336 0.84 AR (0.65) ARPGR
SCHEMBL24684821 0.82 AR (0.63) ARPGR
SCHEMBL7784176 0.81 AR (0.71) ARPGR
SCHEMBL2216099 0.81 AR (0.63) ARPGR
SCHEMBL4027208 0.81 AR (0.74) ARPGR
SCHEMBL4022784 0.80 AR (0.63) ARPGR
SCHEMBL4026199 0.79 AR (0.78) ARPGR
SCHEMBL7783753 0.79 AR (0.77) ARPGR
SCHEMBL29757665 0.78 AR (0.70) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35956-E Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1998-11-10 US disclosed
US-5627201-A Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1997-05-06 US disclosed
US-5411981-A Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1995-05-02 US disclosed