Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.58 |
| ▸ | OXTR | P30559 | 1/20 | 0.57 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562440 | 0.93 | AVPR2 (0.54) | AVPR1AAVPR2OXTR | |
| SCHEMBL8558993 | 0.91 | AVPR2 (0.65) | AVPR1AAVPR2 | |
| SCHEMBL8562180 | 0.89 | AVPR2 (0.72) | AVPR1AAVPR2 | |
| SCHEMBL7340204 | 0.87 | AVPR1A (0.55) | AVPR1AAVPR2AVPR1B | |
| SCHEMBL8561006 | 0.87 | AVPR2 (0.75) | AVPR1AAVPR2OXTR | |
| SCHEMBL8556852 | 0.87 | AVPR1A (0.59) | AVPR1AAVPR2OXTR | |
| SCHEMBL7356474 | 0.86 | AVPR1A (0.77) | AVPR1AAVPR2OXTRAVPR1B | |
| SCHEMBL8556841 | 0.84 | AVPR2 (0.65) | AVPR1AAVPR2 | |
| SCHEMBL8561438 | 0.84 | AVPR2 (0.59) | AVPR1AAVPR2 | |
| SCHEMBL8559866 | 0.84 | AVPR2 (0.65) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |