Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8565218 | 0.99 | HTR6 (0.41) | HTR6ACHENOTUMMCHR1HTR2C | |
| SCHEMBL8565814 | 0.90 | NOTUM (0.39) | NOTUMHTR2CDRD2DRD1FAAH | |
| SCHEMBL8563033 | 0.90 | HTR6 (0.45) | HTR6ACHEMCHR1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL8562266 | 0.89 | NOTUM (0.39) | NOTUMHTR2CDRD2DRD1FAAH | |
| Hydrochloric Acid SCHEMBL8559384 | 0.89 | HTR6 (0.44) | HTR6ACHEMCHR1 | |
| SCHEMBL8566149 | 0.85 | HTR6 (0.39) | HTR6ACHE | |
| SCHEMBL8563454 | 0.84 | HTR6 (0.41) | HTR6 | |
| Hydrochloric Acid SCHEMBL8557446 | 0.84 | HTR6 (0.38) | HTR6ACHE | |
| Hydrochloric Acid SCHEMBL8559770 | 0.83 | HTR6 (0.40) | HTR6ACHEMCHR1HTR2C | |
| Acetic Acid SCHEMBL8562511 | 0.83 | HTR6 (0.40) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |