Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8559384 | 0.99 | HTR6 (0.44) | HTR6ACHECTSGCMA1MCHR1 | |
| SCHEMBL8563454 | 0.94 | HTR6 (0.41) | HTR6CTSGCMA1TSHR | |
| Acetic Acid SCHEMBL8562511 | 0.93 | HTR6 (0.40) | HTR6CTSGCMA1 | |
| SCHEMBL8558617 | 0.90 | HTR6 (0.42) | HTR6ACHEMCHR1DRD2DRD1 | |
| SCHEMBL8559521 | 0.89 | TMEM97 (0.39) | CTSGCMA1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL8565218 | 0.89 | HTR6 (0.41) | HTR6ACHEMCHR1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL8563489 | 0.89 | TMEM97 (0.38) | CTSGCMA1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL8559770 | 0.86 | HTR6 (0.40) | HTR6ACHEMCHR1ALDH1A1 | |
| SCHEMBL8566149 | 0.84 | HTR6 (0.39) | HTR6ACHE | |
| SCHEMBL8575396 | 0.83 | CTSG (0.36) | CTSGCMA1TSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |