Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556856 | 0.83 | NR1I2 (0.33) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL9090697 | 0.79 | NPC1 (0.46) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL8220320 | 0.73 | SMN1; SMN2 (0.60) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL8558634 | 0.67 | NPC1 (0.41) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL4503625 | 0.67 | NPC1 (0.55) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL5192240 | 0.66 | LTA4H (0.64) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL13846211 | 0.66 | KMT2A (0.60) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL10507690 | 0.66 | CYP1A2 (0.44) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL8807192 | 0.66 | MAOB (0.70) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL13846113 | 0.64 | NPC1 (0.52) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |