Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 9/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556858 | 0.82 | — | — | |
| SCHEMBL19771902 | 0.70 | KMT2A (0.47) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8220320 | 0.69 | SMN1; SMN2 (0.60) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL9090697 | 0.68 | NPC1 (0.46) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8558630 | 0.67 | NPC1 (0.45) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL5192240 | 0.67 | LTA4H (0.64) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL13846211 | 0.67 | KMT2A (0.60) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL12896173 | 0.63 | NPC1 (0.50) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8551731 | 0.63 | SMN1; SMN2 (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL13846113 | 0.62 | NPC1 (0.52) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |