Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371092 | 0.89 | TSHR (0.54) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL8488580 | 0.83 | IDO1 (0.39) | KDM4EALDH1A1CHRM3LMNAMEN1 | |
| SCHEMBL9187528 | 0.83 | TACR1 (0.41) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL9187515 | 0.83 | TACR1 (0.41) | TSHRTACR1KDM4EPOLBALDH1A1 | |
| SCHEMBL27620254 | 0.83 | TSHR (0.47) | TSHRTACR1ALDH1A1CA1CA2 | |
| SCHEMBL7404874 | 0.81 | TSHR (0.45) | TSHRTACR1LMNAMEN1KMT2A | |
| SCHEMBL8351161 | 0.79 | PRKCA (0.43) | TSHRTACR1KDM4EPOLBGRM5 | |
| SCHEMBL8351167 | 0.79 | PRKCA (0.43) | TSHRTACR1KDM4EPOLBGRM5 | |
| SCHEMBL879875 | 0.79 | UGCG (0.43) | TSHRCHRM3CHRM2CHRM1SLC6A2 | |
| SCHEMBL879889 | 0.79 | UGCG (0.43) | TSHRCHRM3CHRM2CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837868-A | REACTION OF DIHYDROXY OLEFINS IN A MULTISTAGE PROCESS ARYL METHYLAMINE TO FORM PYRROLIDINE INTERMEDIATE | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | disclosed |
| US-5703244-A | CYCLIZATION OF DIHYDROXY OLEFINS WITH TARTRATE ESTER IN PRESENCE OF TITANIUM ISOPROPOXIDE AND TERT-BUTYL HYDROPEROXIDE | ABBOTT LABORATORIES (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0422897-A2 | Recovery of water-insoluble epoxy alcohols | ARCO Chemical Technology, L.P. (US) | 1991-04-17 | — | — | EP | disclosed |