Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 5/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 5/20 | 0.43 |
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | LCT | P09848 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879875 | 1.00 | UGCG (0.43) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL27274916 | 0.79 | L3MBTL1 (0.48) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL8558732 | 0.79 | TSHR (0.47) | TSHRCHRM2CHRM1CHRM3SLC6A2 | |
| SCHEMBL9011624 | 0.76 | TSHR (0.67) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL9011646 | 0.76 | TSHR (0.67) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL9011734 | 0.76 | TSHR (0.67) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL9011715 | 0.76 | TSHR (0.67) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL851490 | 0.75 | SOAT1 (0.54) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL879884 | 0.75 | SOAT1 (0.54) | UGCGGBA2GBA1EPHX2L3MBTL1 | |
| SCHEMBL25208054 | 0.74 | L3MBTL1 (0.54) | UGCGGBA2GBA1EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |