Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915056 | 0.78 | KDM4E (0.50) | KDM4EMEN1KMT2AALDH1A1ADRA2B | |
| SCHEMBL9626409 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1ADRA2BMAPK1DRD3 | |
| SCHEMBL8561725 | 0.76 | CYP1A2 (0.38) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8559994 | 0.75 | CYP1A2 (0.40) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10924522 | 0.75 | MEN1 (0.48) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10764483 | 0.75 | KDM4E (0.32) | KDM4E | |
| SCHEMBL5736019 | 0.74 | KDM4E (0.41) | KDM4EMEN1KMT2AALDH1A1ADRA2B | |
| SCHEMBL10913555 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8559738 | 0.71 | KDM4E (0.39) | KDM4EKMT2AALDH1A1ADRA2BMAPK1 | |
| SCHEMBL10975670 | 0.71 | HPGD (0.34) | KDM4EMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828715-A1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AG (DE) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038417-A1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-05 | — | — | WO | disclosed |