Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158098 | 0.95 | BID (0.51) | BIDMCL1BCL2L1BAK1MAPT | |
| SCHEMBL5685695 | 0.90 | MAPT (0.42) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL30742732 | 0.90 | MAPT (0.42) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL7157314 | 0.87 | G6PD (0.53) | BIDMCL1BCL2L1BAK1MAPT | |
| SCHEMBL10796955 | 0.85 | G6PD (0.51) | BIDMCL1BCL2L1BAK1MAPT | |
| SCHEMBL3831276 | 0.85 | KDM4E (0.41) | MAPTMEN1LMNAKMT2AHSD17B10 | |
| SCHEMBL1002853 | 0.84 | MAPT (0.53) | BIDMCL1BCL2L1BAK1MAPT | |
| SCHEMBL3622854 | 0.84 | PARP1 (0.47) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL10796965 | 0.84 | BID (0.43) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL3824069 | 0.83 | KDM4E (0.40) | BIDMCL1BCL2L1BAK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073552-C | Benzamides for neurodegenerative disorder treatment | CENTAUR PHARMACEUTICALS INC (US) | 2001-10-24 | — | — | CN | disclosed |
| EP-0929525-A2 | NOVEL HETEROARYLOXYETHYLAMINES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | disclosed |
| CN-1182416-A | Benzamides for neurodegenerative disorder treatment | CENTAUR PHARMACUETICALS INC (US) | 1998-05-20 | — | — | CN | disclosed |
| WO-1998013349-A2 | HETEROARYLOXYETHYLAMINES AS 5-HT1A LIGANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | disclosed |