Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555519 | 0.84 | CHRNB2 (0.38) | KMT2AMAPTALDH1A1TDP1CHRNB2 | |
| SCHEMBL8557069 | 0.81 | HRH4 (0.39) | KMT2AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL6767976 | 0.71 | CHRNB2 (0.37) | CNR1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL1961848 | 0.70 | APOBEC3A (0.48) | KMT2AMAPTGAAPOLBNPC1 | |
| Water SCHEMBL4082000 | 0.68 | APOBEC3A (0.47) | KMT2AMAPTGAAPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL10751415 | 0.68 | APOBEC3A (0.47) | KMT2AMAPTGAAPOLBNPC1 | |
| Bromide SCHEMBL10751445 | 0.68 | APOBEC3A (0.47) | KMT2AMAPTALDH1A1GAAPOLB | |
| SCHEMBL10257015 | 0.68 | APOBEC3A (0.47) | KMT2AMAPTGAALMNAPOLB | |
| Hydrochloric Acid SCHEMBL9771635 | 0.67 | CHRNB2 (0.39) | CNR1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL30066585 | 0.65 | CYP2A6 (0.50) | MAPTALDH1A1TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685456-B1 | Bisquaternary ammonium derivatives of 2,2'-dimethyl-1,1'binaphtyl and process for their preparation | HOECHST AG (DE) | 1998-04-15 | — | — | EP | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | claimed |
| US-5599989-A | Bisquaternary ammonium compounds of 2,2'-dimethyl-1,1'-binaphythyl and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |