Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.60 |
| ▸ | OXTR | P30559 | 2/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556628 | 0.91 | AVPR2 (0.53) | AVPR2OXTRAVPR1ANPC1HPGD | |
| SCHEMBL8556989 | 0.91 | AVPR1A (0.72) | AVPR2OXTRAVPR1A | |
| SCHEMBL8559258 | 0.90 | AVPR2 (0.58) | AVPR2OXTRAVPR1A | |
| SCHEMBL8685905 | 0.90 | AVPR2 (0.57) | AVPR2OXTRAVPR1A | |
| SCHEMBL8557460 | 0.87 | AVPR1A (0.64) | AVPR2OXTRAVPR1A | |
| SCHEMBL8559570 | 0.85 | AVPR1A (0.55) | AVPR2OXTRAVPR1ANPC1HPGD | |
| SCHEMBL8559975 | 0.85 | AVPR2 (0.58) | AVPR2OXTRAVPR1ANPC1HPGD | |
| SCHEMBL8558289 | 0.84 | AVPR2 (0.60) | AVPR2OXTRAVPR1ARAB9A | |
| SCHEMBL8563752 | 0.84 | ALDH1A1 (0.57) | AVPR2OXTRAVPR1A | |
| SCHEMBL8557290 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |