Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 10/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935799 | 0.84 | GABRG2 (0.51) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL8895490 | 0.81 | KMT2A (0.50) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL4963197 | 0.81 | TP53 (0.58) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL21621661 | 0.81 | GABRG2 (0.47) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL7508053 | 0.80 | MAPT (0.47) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL21979193 | 0.78 | PDE4D (0.53) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL14692520 | 0.78 | PDE4B (0.46) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL28685593 | 0.77 | PDE4B (0.50) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL23611832 | 0.77 | BRD4 (0.45) | GABRG2GABRB3GABRA5GABRA2GABRA1 | |
| SCHEMBL11887387 | 0.77 | GABRG2 (0.44) | GABRG2GABRB3GABRA5GABRA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041928-C | Imidazoloquinoxalinone derivatives as eaa antagonists | BASF AG (DE) | 1999-02-03 | — | — | CN | disclosed |
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |
| CN-1120336-A | Imidazoloquinoxalinone derivatives as eaa antagonists | BASF AG (DE) | 1996-04-10 | — | — | CN | disclosed |
| EP-0691970-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022865-A1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |