Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893127 | 0.83 | MAPK1 (0.45) | KMT2ARAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL8558986 | 0.81 | GABRG2 (0.51) | KDM4EGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL16935799 | 0.76 | GABRG2 (0.51) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL4963197 | 0.75 | TP53 (0.58) | RAB9ANPC1KDM4EGABRG2GABRB3 | |
| SCHEMBL23611832 | 0.74 | BRD4 (0.45) | RAB9AGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL21979193 | 0.73 | PDE4D (0.53) | RAB9ANPC1KDM4EGABRG2GABRB3 | |
| SCHEMBL21621661 | 0.72 | GABRG2 (0.47) | GABRG2GABRB3GABRA5GABRA1GABRA3 | |
| SCHEMBL14692520 | 0.72 | PDE4B (0.46) | KMT2AGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4122649 | 0.72 | KMT2A (0.58) | KMT2ARAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL15110383 | 0.72 | KMT2A (0.67) | KMT2ARAB9ANPC1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034896-A1 | NOVEL HETEROCYCLICALLY SUBSTITUTED IMIDAZOLOQUINOXALINONES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-25 | — | — | WO | disclosed |