Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597240 | 0.84 | TDP1 (0.59) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL26127977 | 0.84 | TDP1 (0.59) | NPC1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL16242051 | 0.83 | NPC1 (0.56) | NPC1RAB9ALTA4HALDH1A1PLAU | |
| SCHEMBL28683220 | 0.83 | KMT2A (0.50) | NPC1RAB9AALDH1A1ALOX12MAPT | |
| SCHEMBL10518901 | 0.82 | LMNA (0.62) | ALDH1A1CYP1A2CYP2C19MAPTMEN1 | |
| SCHEMBL8557978 | 0.81 | CA1 (0.62) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL7898710 | 0.80 | NPC1 (0.54) | NPC1RAB9ALTA4HALDH1A1PLAU | |
| SCHEMBL2704247 | 0.80 | KMT2A (0.71) | NPC1RAB9AALDH1A1PLAUELANE | |
| Toluene SCHEMBL29087078 | 0.79 | KMT2A (0.50) | NPC1RAB9AALDH1A1ALOX12MAPT | |
| SCHEMBL1267118 | 0.79 | NPC1 (0.58) | NPC1RAB9AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811456-A | TREATMENT OF ALZHEIMER'S DISEASE | LABORATOIRES MAYOLY SPINDLER (FR) | 1998-09-22 | — | — | US | disclosed |
| EP-0586379-B1 | POLYMERISATION REGULATION | COMMW SCIENT IND RES ORG (AU) | 1998-05-20 | — | — | EP | disclosed |
| US-5739228-A | Polymerization using thionoester compounds as chain transfer agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1998-04-14 | — | — | US | disclosed |
| EP-0586379-A1 | POLYMERISATION REGULATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-03-16 | — | — | EP | disclosed |
| EP-0586379-A4 | POLYMERISATION REGULATION. | COMMW SCIENT IND RES ORG (AU) | 1993-12-10 | — | — | EP | disclosed |
| WO-1992013903-A1 | POLYMERISATION REGULATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1992-08-20 | — | — | WO | disclosed |