Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26127977 | 1.00 | TDP1 (0.59) | TDP1KMT2ACA12CA1CA2 | |
| Thiobenzoic Acid SCHEMBL36460 | 0.94 | TDP1 (0.53) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL28683220 | 0.91 | KMT2A (0.50) | TDP1KMT2ACA12CA1CA2 | |
| Thiobenzoic Acid SCHEMBL23927738 | 0.91 | TDP1 (0.50) | TDP1KMT2ACA12CA1CA2 | |
| Toluene SCHEMBL29087078 | 0.91 | KMT2A (0.50) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL10518901 | 0.90 | LMNA (0.62) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL8560951 | 0.88 | KMT2A (0.47) | TDP1KMT2ACA12CA1CA2 | |
| Thiobenzoic Acid SCHEMBL28352009 | 0.85 | ALDH1A1 (0.47) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL8558996 | 0.84 | NPC1 (0.54) | TDP1KMT2ACA12CA1CA2 | |
| SCHEMBL15282039 | 0.82 | NR4A1 (0.54) | TDP1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102942661-B | Intelligent thermo-sensitive glycosyl hydrogel with dumbbell structure and preparation method of hydrogel | UNIV NANTONG | 2014-07-09 | — | — | CN | claimed |
| CN-102964547-A | PH response glycosyl intelligent hydrogel with segmented structure and preparation method thereof | UNIV NANTONG | 2013-03-13 | — | — | CN | claimed |
| CN-102942661-A | Intelligent thermo-sensitive glycosyl hydrogel with dumbbell structure and preparation method of hydrogel | UNIV NANTONG | 2013-02-27 | — | — | CN | claimed |
| CN-102731354-A | Preparation and plant growth-regulating activity of water-oil soluble o-(4-chloro) benzylthio-benzoate derivatives | UNIV NANKAI | 2012-10-17 | — | — | CN | claimed |
| CN-100366646-C | Polymer charge-conveying materials and preparing method thereof | UNIV FUDAN (CN) | 2008-02-06 | — | — | CN | claimed |
| EP-1136521-B1 | Process for preparing an ocular lens material having hydrophilic surface | MENICON CO LTD (JP) | 2007-02-21 | — | — | EP | claimed |
| CN-1869081-A | Method of one step synthesizing star polymer by free radical polymerization | CHINESE ACAD INST CHEMISTRY (CN) | 2006-11-29 | — | — | CN | claimed |
| US-6533415-B2 | Ocular lens material having hydrophilic surface and process for preparing the same | MENICON CO., LTD. (JP) | 2003-03-18 | — | — | US | claimed |
| US-20010050749-A1 | Ocular lens material having hydrophilic surface and process for preparing the same | MENICON CO., LTD. (JP) | 2001-12-13 | — | — | US | claimed |
| EP-1136521-A2 | Ocular lens material having hydrophilic surface and process for preparing the same | Menicon Co., Ltd. (JP) | 2001-09-26 | — | — | EP | claimed |
| CN-113620764-B | Preparation method of sulfonyl thioester | 武汉瑞晟药业有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-11078157-B1 | Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same | UNIVERSITY OF OREGON (US) | 2021-08-03 | — | — | US | disclosed |
| CN-109721694-A | Segmented copolymer and its preparation method and application and lubricant compositions | 中国石油化工股份有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-109721696-A | Di-block copolymer and its preparation method and application and lubricant compositions | 中国石油化工股份有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-109721695-A | Block copolymer and its preparation method and application and nylon/PPS intermingling material | 中国石油化工股份有限公司 | 2019-05-07 | — | — | CN | disclosed |
| EP-0586379-B1 | POLYMERISATION REGULATION | COMMW SCIENT IND RES ORG (AU) | 1998-05-20 | — | — | EP | disclosed |
| US-5739228-A | Polymerization using thionoester compounds as chain transfer agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1998-04-14 | — | — | US | disclosed |
| EP-0586379-A1 | POLYMERISATION REGULATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-03-16 | — | — | EP | disclosed |
| EP-0586379-A4 | POLYMERISATION REGULATION. | COMMW SCIENT IND RES ORG (AU) | 1993-12-10 | — | — | EP | disclosed |
| WO-1992013903-A1 | POLYMERISATION REGULATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1992-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078157-B1 | Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same | CBS, SQOR, QSOX1 | TDP1 2554/4885KMT2A 2108/4885CA12 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.