Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.75 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.75 |
| ▸ | PYGL | P06737 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315535 | 0.86 | AVPR2 (1.00) | AVPR2AVPR1A | |
| SCHEMBL8560580 | 0.85 | AVPR2 (0.56) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8563344 | 0.83 | AVPR2 (0.81) | AVPR2AVPR1A | |
| SCHEMBL8557743 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1AACHE | |
| SCHEMBL8561097 | 0.83 | AVPR2 (0.52) | AVPR2AVPR1AHDAC1HDAC8HDAC6 | |
| SCHEMBL8557275 | 0.82 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8561645 | 0.81 | AVPR2 (0.58) | AVPR2AVPR1AKDM4EACHE | |
| SCHEMBL8558085 | 0.81 | AVPR2 (0.61) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8556252 | 0.80 | NAMPT (0.63) | AVPR2AVPR1AKDM4EALDH1A1 | |
| SCHEMBL8562554 | 0.79 | AVPR2 (0.73) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |