Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557275 | 0.90 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8559006 | 0.85 | AVPR2 (0.75) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8317076 | 0.85 | AVPR2 (0.77) | AVPR2AVPR1A | |
| SCHEMBL8556252 | 0.83 | NAMPT (0.63) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8560800 | 0.82 | AVPR2 (0.79) | AVPR2AVPR1AOXTR | |
| SCHEMBL8561403 | 0.81 | AVPR2 (0.60) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558857 | 0.81 | HPGD (0.57) | ALDH1A1 | |
| SCHEMBL8562010 | 0.78 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL8562598 | 0.78 | PDE4A (0.54) | AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8562633 | 0.78 | AVPR2 (0.55) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |