Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559546 | 0.92 | AVPR2 (0.55) | AVPR2AVPR1ANPSR1ACHE | |
| SCHEMBL8557607 | 0.89 | NPC1 (0.50) | AVPR2AVPR1ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL8561097 | 0.85 | AVPR2 (0.52) | AVPR2AVPR1ANPC1RAB9A | |
| SCHEMBL8557503 | 0.84 | ACHE (0.58) | AVPR2AVPR1ANPC1RAB9AACHE | |
| SCHEMBL8563344 | 0.83 | AVPR2 (0.81) | AVPR2AVPR1A | |
| SCHEMBL8558027 | 0.81 | AVPR2 (0.69) | AVPR2AVPR1A | |
| SCHEMBL8559006 | 0.81 | AVPR2 (0.75) | AVPR2AVPR1AKDM4EACHE | |
| SCHEMBL8563565 | 0.81 | NAMPT (0.50) | AVPR2AVPR1AKDM4ENPC1RAB9A | |
| SCHEMBL8562097 | 0.81 | AVPR2 (0.49) | AVPR2AVPR1ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL8559349 | 0.81 | AVPR2 (0.60) | AVPR2AVPR1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |