Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.46 |
| ▸ | RB1 | P06400 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655639 | 0.95 | HTR1D (0.50) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| SCHEMBL7654350 | 0.88 | HTR1D (0.51) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| SCHEMBL7659740 | 0.86 | HTR1A (0.52) | HTR1DHTR1BRB1 | |
| SCHEMBL7662787 | 0.85 | HTR1B (0.53) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| SCHEMBL7656208 | 0.85 | EGFR (0.53) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| SCHEMBL8555902 | 0.82 | HTR1A (0.47) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL8604088 | 0.81 | EGFR (0.44) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| SCHEMBL7663796 | 0.80 | HTR2A (0.51) | EGFRIGF1RFLT4KDRHTR1D | |
| SCHEMBL7655690 | 0.80 | EGFR (0.53) | EGFRIGF1RFLT4KDRMAPKAPK2 | |
| SCHEMBL7657062 | 0.80 | EGFR (0.51) | EGFRIGF1RFLT4KDRMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011895-A1 | A METHOD FOR THE PREVENTION OF MIGRAINE | ELI LILLY AND COMPANY (US) | 1998-03-26 | — | — | WO | disclosed |
| US-5708187-A | MIGRANE HEADACHES | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |