Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624795 | 0.83 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL4528482 | 0.71 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL7869969 | 0.70 | — | — | |
| SCHEMBL7869156 | 0.70 | — | — | |
| SCHEMBL7383796 | 0.70 | — | — | |
| SCHEMBL8425985 | 0.70 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL708400 | 0.69 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL5073221 | 0.69 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL2008257 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL28914670 | 0.68 | RIPK1 (0.38) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695755-B1 | Pyrrolocarbazole | HOFFMANN LA ROCHE (CH) | 1998-10-21 | — | — | EP | disclosed |
| US-5721267-A | ANTICANCER AGENTS | SYNTEX (U.S.A.) INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0695755-A1 | Pyrrolocarbazoles | F. Hoffmann-La Roche AG (CH) | 1996-02-07 | — | — | EP | disclosed |
| US-5405864-A | Chemotherapeutic maleimides | SYNTEX (U.S.A.) INC. (US) | 1995-04-11 | — | — | US | disclosed |