Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528482 | 0.94 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL8391276 | 0.80 | — | — | |
| SCHEMBL19305259 | 0.76 | — | — | |
| SCHEMBL8070765 | 0.69 | PPARA (0.33) | RIPK1 | |
| SCHEMBL8559419 | 0.69 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL9569520 | 0.68 | ATM (0.30) | — | |
| SCHEMBL702654 | 0.68 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL5079143 | 0.68 | PPARA (0.39) | — | |
| SCHEMBL8075407 | 0.68 | PPARA (0.36) | RIPK1 | |
| SCHEMBL28914670 | 0.67 | RIPK1 (0.38) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348173-B2 | Fatty-acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-25 | — | — | US | disclosed |
| EP-0970195-B1 | FATTY-ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-0833899-B1 | CIS-9,10-OCTADECENOAMIDASE | SCRIPPS RESEARCH INST (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20040265958-A1 | that hydrolyzes fatty amides such as cis-9,10-octadecenoamide to neutralize the soporific activity of the fatty amides; enzyme inhibitors for use in treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE | 2004-12-30 | — | — | US | disclosed |
| US-6699682-B2 | ENZYMATIC POLYPEPTIDE FOR USE IN THE TREATMENT OF SLEEP DISORDERS | THE SCRIPPS RESEARCH INSTITUTE | 2004-03-02 | — | — | US | disclosed |
| US-20020187542-A1 | Fatty-acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-12-12 | — | — | US | disclosed |
| EP-0970195-A4 | FATTY-ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6271015-B1 | A POLYPEPTIDE HAVING AN AMINO ACID SEQUENCE THAT HYDROLYSIZES CIS-9,10-OCTADECENOAMIDE AND OTHER SOPORIFIC FATTY ACID AMIDES; THERAPY FOR SLEEP DISORDERS AND NARCOLEPSY | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-07 | — | — | US | disclosed |
| EP-0833899-A4 | CIS-9,10-OCTADECENOAMIDASE | SCRIPPS RESEARCH INST (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0970195-A1 | FATTY-ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998020119-A9 | FATTY-ACID AMIDE HYDROLASE | — | 1998-11-05 | — | — | WO | disclosed |
| WO-1998020119-A1 | FATTY-ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-05-14 | — | — | WO | disclosed |
| EP-0833899-A1 | CIS-9,10-OCTADECENOAMIDASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041869-A1 | CIS-9,10-OCTADECENOAMIDASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040265958-A1 | that hydrolyzes fatty amides such as cis-9,10-octadecenoamide to neutralize the soporific activity of the fatty amides; enzyme inhibitors for use in treating sleep disorders | FAAH, FAAH2, APEH | RIPK1 3506/4885 |
| US-20020187542-A1 | Fatty-acid amide hydrolase | FAAH, FAAH2, APEH | RIPK1 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.