Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 11/20 | 0.35 |
| ▸ | DRD4 | P21917 | 10/20 | 0.35 |
| ▸ | DRD5 | P21918 | 10/20 | 0.35 |
| ▸ | DRD2 | P14416 | 9/20 | 0.35 |
| ▸ | DRD3 | P35462 | 9/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8563487 | 0.99 | HTR6 (0.39) | HTR6TMEM97SIGMAR1NOTUMDRD1 | |
| SCHEMBL8560509 | 0.91 | TMEM97 (0.42) | HTR6TMEM97SIGMAR1NOTUMHRH3 | |
| SCHEMBL8563028 | 0.91 | HTR6 (0.37) | HTR6NOTUMDRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL8561493 | 0.90 | TMEM97 (0.42) | HTR6TMEM97SIGMAR1NOTUMHRH3 | |
| SCHEMBL8565811 | 0.90 | NOTUM (0.40) | HTR6TMEM97SIGMAR1NOTUMDRD1 | |
| Hydrochloric Acid SCHEMBL8559380 | 0.90 | HTR6 (0.36) | HTR6NOTUMDRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL8562261 | 0.89 | NOTUM (0.40) | HTR6TMEM97SIGMAR1NOTUMDRD1 | |
| SCHEMBL8563449 | 0.87 | HTR6 (0.36) | HTR6NOTUM | |
| SCHEMBL8558612 | 0.81 | NOTUM (0.36) | HTR6NOTUMDRD1DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL8565214 | 0.80 | NOTUM (0.36) | HTR6NOTUMDRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |