Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8559380 | 0.99 | HTR6 (0.36) | HTR6NOTUMACHEMCHR1DRD2 | |
| SCHEMBL8563449 | 0.94 | HTR6 (0.36) | HTR6NOTUM | |
| SCHEMBL8559515 | 0.91 | HTR6 (0.39) | HTR6NOTUMDRD2DRD1DRD4 | |
| SCHEMBL8558612 | 0.90 | NOTUM (0.36) | HTR6NOTUMACHEMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL8563487 | 0.90 | HTR6 (0.39) | HTR6NOTUMDRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL8565214 | 0.89 | NOTUM (0.36) | HTR6NOTUMACHEMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL8559768 | 0.85 | ALDH1A1 (0.36) | HTR6ACHEMCHR1DRD2DRD1 | |
| SCHEMBL8566144 | 0.84 | PTGER1 (0.34) | HTR6 | |
| Hydrochloric Acid SCHEMBL8557445 | 0.83 | PTGER1 (0.35) | HTR6 | |
| SCHEMBL8560509 | 0.81 | TMEM97 (0.42) | HTR6NOTUMHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |