Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5085462 | 0.84 | GABRA1 (0.31) | — | |
| SCHEMBL6831030 | 0.82 | GABRA1 (0.32) | — | |
| SCHEMBL12387626 | 0.80 | GABRA1 (0.33) | — | |
| SCHEMBL12387633 | 0.80 | GABRA1 (0.33) | — | |
| Iodide SCHEMBL5085340 | 0.80 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2965190 | 0.80 | GABRA1 (0.31) | — | |
| SCHEMBL14370241 | 0.73 | PRKCI (0.33) | — | |
| SCHEMBL14993279 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL166573 | 0.72 | GABRA1 (0.41) | — | |
| SCHEMBL29619533 | 0.72 | GABRA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958906-A | Phospholipid derivatives containing higher elements of the fifth main group | ASTA-MEDICA AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5637577-A | TREATMENT OF POTOZOAL DISEASES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5449798-A | Phospholipid derivatives containing higher elements of the fifth group | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1995-09-12 | — | — | US | disclosed |