Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559598 | 1.00 | ALOX5 (0.55) | ALOX5PDE10ANPC1MAPTRAB9A | |
| SCHEMBL8557021 | 0.80 | ALOX5 (0.52) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8554925 | 0.79 | GPBAR1 (0.61) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555246 | 0.79 | GPBAR1 (0.61) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555687 | 0.78 | GPBAR1 (0.60) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL8555104 | 0.78 | GPBAR1 (0.60) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL10547054 | 0.78 | NPC1 (0.59) | ALOX5PDE10ANPC1MAPTRAB9A | |
| SCHEMBL8559593 | 0.78 | ALOX5 (0.72) | ALOX5PDE10A | |
| SCHEMBL8626714 | 0.77 | NPC1 (0.60) | ALOX5NPC1MAPTRAB9AALOX5AP | |
| SCHEMBL8626737 | 0.77 | NPC1 (0.60) | ALOX5NPC1MAPTRAB9AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |