⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8931631 | 0.97 | — | — | |
| SCHEMBL8608073 | 0.97 | — | — | |
| SCHEMBL5678718 | 0.88 | — | — | |
| SCHEMBL856336 | 0.73 | GRIN2D (0.33) | — | |
| SCHEMBL3671124 | 0.71 | — | — | |
| SCHEMBL969840 | 0.71 | — | — | |
| SCHEMBL855924 | 0.71 | GRIN2D (0.35) | — | |
| SCHEMBL10914880 | 0.69 | DNM1 (0.36) | — | |
| SCHEMBL19883241 | 0.69 | — | — | |
| SCHEMBL12997286 | 0.69 | DNM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820776-B2 | Process for the preparation of Remimazolam and solid state forms of Remimazolam salts | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2023-11-21 | — | — | US | claimed |
| US-20210277013-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2021-09-09 | — | — | US | claimed |
| WO-2018148361-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS | WATSON LABORATORIES INC. (US) | 2018-08-16 | — | — | WO | claimed |
| US-11820776-B2 | Process for the preparation of Remimazolam and solid state forms of Remimazolam salts | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2023-11-21 | — | — | US | disclosed |
| US-20210277013-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2021-09-09 | — | — | US | disclosed |
| US-11034697-B2 | Process for the preparation of Remimazolam and solid state forms of Remimazolam salts | WATSON LABORATORIES INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-10428083-B2 | Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-01 | — | — | US | disclosed |
| US-10363340-B2 | Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof | MCMASTER UNIVERSITY (CA) | 2019-07-30 | — | — | US | disclosed |
| EP-3274352-B1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | Bayer Pharma AG (DE) | 2019-01-02 | — | — | EP | disclosed |
| WO-2018160855-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2018-09-07 | — | — | WO | disclosed |
| WO-2018148361-A1 | PROCESS FOR THE PREPARATION OF REMIMAZOLAM AND SOLID STATE FORMS OF REMIMAZOLAM SALTS | WATSON LABORATORIES INC. (US) | 2018-08-16 | — | — | WO | disclosed |
| US-5114940-A | Insecticides or anthelmintics from fused ring heterocycles containing amides or thioamides | ROUSSEL-UCLAF (FR) | 1992-05-19 | — | — | US | disclosed |
| EP-0317188-A2 | Heteroaromatic enamide derivatives and their use as pesticides | ROUSSEL UCLAF (FR) | 1989-05-24 | — | — | EP | disclosed |
| EP-0254245-A1 | Hetrazepins and processes for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1988-01-27 | — | — | EP | disclosed |
| US-4569934-A | ANTIANXIETY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0068806-A2 | Basic acyl amides of (5-amino-1,3-dialkylpyrazol-4-yl)(aryl)methanones, processes for their production, and pharmaceutical compositions containing such compounds | WARNER-LAMBERT COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |
| US-4150139-A | MUSCLE RELAXANTS, ANALGESICS, ANTIINFLAMMATORY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-17 | — | — | US | disclosed |
| US-3992400-A | 1-(α-Phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3941802-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |