SCHEMBL856336

SCHEMBL856336

CC1(CCCN)OCCO1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL855924 0.93 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10914880 0.91 DNM1 (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12997286 0.91 DNM1 (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29234768 0.91 GRIN2D (0.31) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL254457 0.75
SCHEMBL253950 0.75
SCHEMBL13361696 0.75
SCHEMBL8566999 0.75
SCHEMBL18322828 0.75
SCHEMBL506092 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605461-B2 Hydrogel compositions and uses thereof Shoichet, Molly Sandra (CA) 2026-04-21 US disclosed
CN-114466869-B Hydrogel composition and use thereof 莫莉·桑德拉·萧伊凯特 2024-03-19 CN disclosed
US-20230364025-A1 PROTEIN-RELEASE SYSTEM FOR SUSTAINED RELEASE OF PROTEINS ISAACS BERNAL DANIELA FERNANDA (CA) 2023-11-16 US disclosed
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET, MOLLY SANDRA (CA) 2023-05-04 US disclosed
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET, MOLLY SANDRA (CA) 2023-05-04 US disclosed
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET, MOLLY SANDRA (CA) 2023-05-04 US disclosed
EP-3994183-A1 HYDROGEL COMPOSITIONS AND USES THEREOF Shoichet, Molly Sandra (CA) 2022-05-11 EP disclosed
CN-114466869-A Hydrogel composition and use thereof 莫莉·桑德拉·萧伊凯特 2022-05-10 CN disclosed
WO-2021000050-A1 HYDROGEL COMPOSITIONS AND USES THEREOF SHOICHET MOLLY SANDRA (CA) 2021-01-07 WO disclosed
US-9765071-B2 Substituted imidazo ring systems and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-09-19 US disclosed
WO-2005051324-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-09 WO disclosed
WO-2005051317-A2 SUBSTITUTED IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-09 WO disclosed
US-6812349-B2 MATERIALS FOR SYNTHESIS PEPTIC ULCER MEDICAMENTS; SUCH AS 2-CYANO-4,5-DIMETHYL-1-N-(PENTAN-2-ON-5-YL)IMIDAZOLE ALTANA PHARMA AG (DE) 2004-11-02 US disclosed
US-6716990-B2 TREATMENT OF PEPTIC ULCERS ALTANA PHARMA AG (DE) 2004-04-06 US disclosed
US-20040059127-A1 Process and intermediates for the preparation of imidazopyridines BYK GULDEN FABRIK LOMBERG CHEMISCHE FABRIK GMBH (DE) 2004-03-25 US disclosed
US-20030004358-A1 Process and intermediates for the preparation of imidazopyridines ALTANA PHARMA AG (DE) 2003-01-02 US disclosed
EP-1250335-A2 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF IMIDAZOPYRIDINES ALTANA Pharma AG (DE) 2002-10-23 EP disclosed
WO-2001051486-A2 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF IMIDAZOPYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2001-07-19 WO disclosed
US-4167632-A APPETITE SUPPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1979-09-11 US disclosed
US-4122265-A APPETITE SUPPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1978-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133656-A1 HYDROGEL COMPOSITIONS AND USES THEREOF CD44, UACA, ALDH1A2 GRIN2D 1935/4885GRIN3B 3053/4885GRIN1 2476/4885
US-20030004358-A1 Process and intermediates for the preparation of imidazopyridines CYP3A4, CYP1A1, CYP1A2 GRIN2D 2345/4885GRIN3B 2708/4885GRIN1 1351/4885
US-20040059127-A1 Process and intermediates for the preparation of imidazopyridines CYP3A4, CYP1A2, CYP1A1 GRIN2D 2978/4885GRIN3B 3087/4885GRIN1 1696/4885
US-12605461-B2 Hydrogel compositions and uses thereof CD44, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, COL1A1 GRIN2D 880/4885GRIN3B 2054/4885GRIN1 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.