SCHEMBL8559826

SCHEMBL8559826

CCCC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Cl)c(C)nc23)c1Cl

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 10/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8560297 0.99 BDKRB2 (0.84) BDKRB2
SCHEMBL8565579 0.92 BDKRB2 (1.00) BDKRB2
Hydrochloric Acid SCHEMBL8563441 0.92 BDKRB2 (0.98) BDKRB2
SCHEMBL8565007 0.91 BDKRB2 (0.72) BDKRB2
Hydrochloric Acid SCHEMBL8563666 0.91 BDKRB2 (0.72) BDKRB2
SCHEMBL8567767 0.90 BDKRB2 (0.85) BDKRB2
Hydrochloric Acid SCHEMBL8564124 0.89 BDKRB2 (0.84) BDKRB2
Hydrochloric Acid SCHEMBL8564608 0.88 BDKRB2 (0.86) BDKRB2
SCHEMBL8566314 0.88 BDKRB2 (0.96) BDKRB2
SCHEMBL8561923 0.87 BDKRB2 (1.00) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596406-B1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO (JP) 1998-12-16 EP disclosed
US-5574042-A ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN FUJISAWA PHARMACEUTICAL CO., LTD (JP) 1996-11-12 US disclosed
EP-0596406-A1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-11 EP disclosed