SCHEMBL8559940

SCHEMBL8559940

CC(=O)NCC(=O)Nc1ccc(/C=C/C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Cl)c(C)nc34)c2Cl)cc1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559941 1.00 BDKRB2 (0.80) BDKRB2
Hydrochloric Acid SCHEMBL8565393 0.99 BDKRB2 (0.80) BDKRB2
Hydrochloric Acid SCHEMBL8565389 0.99 BDKRB2 (0.80) BDKRB2
SCHEMBL8567472 0.95 BDKRB2 (0.88) BDKRB2
SCHEMBL8567475 0.95 BDKRB2 (0.88) BDKRB2
Hydrochloric Acid SCHEMBL8564959 0.95 BDKRB2 (0.88) BDKRB2
Hydrochloric Acid SCHEMBL8564960 0.95 BDKRB2 (0.88) BDKRB2
SCHEMBL8562978 0.94 BDKRB2 (0.77) BDKRB2
SCHEMBL8565041 0.94 BDKRB2 (0.91) BDKRB2
SCHEMBL8565043 0.94 BDKRB2 (0.91) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596406-B1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO (JP) 1998-12-16 EP disclosed
EP-0596406-A1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-11 EP disclosed