Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557594 | 0.99 | HTR1A (0.62) | HTR1AMAOB | |
| SCHEMBL8554502 | 0.93 | HTR1A (0.68) | HTR1AMAOB | |
| SCHEMBL3174057 | 0.91 | HTR1A (0.68) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL2687983 | 0.91 | HTR1A (0.70) | HTR1AMAOB | |
| SCHEMBL8557005 | 0.91 | HTR1A (0.70) | HTR1AMAOB | |
| SCHEMBL12124720 | 0.91 | HTR1A (0.68) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL6339624 | 0.89 | HTR1A (0.69) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL2362765 | 0.88 | HTR1A (0.68) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL5824979 | 0.88 | HTR1A (0.68) | HTR1AMAOBDRD2DRD3 | |
| SCHEMBL1569172 | 0.86 | HTR1A (0.69) | HTR1AMAOBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |