Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989735 | 0.69 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL5527216 | 0.69 | KDM4E (0.72) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| Phthalic Acid SCHEMBL3640036 | 0.68 | ALDH1A1 (0.52) | MAPTKDM4EALDH1A1USP2TSHR | |
| SCHEMBL29793010 | 0.68 | RECQL (0.41) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL10002464 | 0.67 | PIK3CG (1.00) | PIK3CGMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL5257182 | 0.67 | MYC (0.39) | MAPTKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL8247365 | 0.66 | PIK3CG (0.55) | PIK3CGMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL30428028 | 0.65 | MYC (0.50) | KDM4EALDH1A1HPGDUSP2TSHR | |
| SCHEMBL11378060 | 0.65 | MYC (0.58) | KDM4EALDH1A1RAB9AUSP2TSHR | |
| SCHEMBL31607735 | 0.64 | KDM4E (0.56) | KDM4EALDH1A1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591528-B1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | disclosed |