Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564208 | 0.99 | CHEK1 (0.61) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL8554348 | 0.88 | TSHR (0.61) | P4HTMKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL5584774 | 0.86 | MEN1 (0.53) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL8560118 | 0.86 | MEN1 (0.53) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL5584408 | 0.83 | MEN1 (0.50) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL5584406 | 0.83 | PKM (0.52) | P4HTMKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL12758443 | 0.81 | P4HTM (0.70) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL8907998 | 0.80 | F10 (0.48) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL8908002 | 0.80 | F10 (0.48) | CHEK1PIM1MAPK8CLK4P4HTM | |
| SCHEMBL6834176 | 0.79 | ALB (0.61) | CHEK1PIM1MAPK8CLK4P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756524-A | APPLYING TO COMBAT CYTOPATHOGENIC FUNGI | AGREVO UK LIMITED (GB) | 1998-05-26 | — | — | US | disclosed |
| EP-0750611-A1 | ANILIDE DERIVATIVES AS FUNGICIDES | AgrEvo UK Limited (GB) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025723-A1 | ANILIDE DERIVATIVES AS FUNGICIDES | AGREVO UK LIMITED (GB) | 1995-09-28 | — | — | WO | disclosed |