Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 2/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504076 | 0.83 | CYP19A1 (0.83) | CYP19A1LMNAALDH1A1VCAM1MAPT | |
| SCHEMBL8567922 | 0.80 | ALDH1A1 (0.57) | CYP19A1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL18230026 | 0.77 | CYP19A1 (0.69) | CYP19A1LMNAALDH1A1CA12 | |
| SCHEMBL8559976 | 0.77 | AR (0.44) | CYP19A1LMNAALDH1A1MAPTPKM | |
| SCHEMBL8597802 | 0.77 | ALDH1A1 (0.47) | CYP19A1LMNAALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8567841 | 0.77 | CYP19A1 (0.57) | CYP19A1LMNAALDH1A1VCAM1MAPT | |
| SCHEMBL8566052 | 0.77 | NSD2 (0.49) | CYP19A1LMNAVCAM1SMN1; SMN2MAPT | |
| SCHEMBL22489911 | 0.76 | CYP19A1 (0.73) | CYP19A1LMNAALDH1A1VCAM1CA12 | |
| SCHEMBL8596415 | 0.75 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8567878 | 0.75 | KDM4C (0.57) | LMNAALDH1A1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |