Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.56 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476661 | 0.85 | LMNA (0.70) | CYP19A1LMNAALDH1A1AR | |
| SCHEMBL3374012 | 0.85 | ALDH1A1 (0.80) | CYP19A1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7973043 | 0.85 | LMNA (0.66) | CYP19A1LMNAALDH1A1CA1CA2 | |
| SCHEMBL4181150 | 0.84 | CYP19A1 (0.65) | CYP19A1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL29791528 | 0.84 | CYP19A1 (0.65) | CYP19A1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL18230026 | 0.84 | CYP19A1 (0.69) | CYP19A1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL30649118 | 0.83 | KMT2A (0.71) | CYP19A1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL4389696 | 0.83 | KMT2A (0.71) | CYP19A1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8560152 | 0.83 | CYP19A1 (0.60) | CYP19A1LMNAALDH1A1VCAM1CA12 | |
| SCHEMBL4292760 | 0.82 | ALDH1A1 (0.68) | CYP19A1LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117499-B | Preparation method of alpha aryl amidine imine derivative | 上海应用技术大学 | 2020-10-09 | — | — | CN | claimed |
| CN-108117499-A | A kind of preparation method of α aryl amidine imine derivative | 上海应用技术大学 | 2018-06-05 | — | — | CN | claimed |
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108117499-A | A kind of preparation method of α aryl amidine imine derivative | 上海应用技术大学 | 2018-06-05 | — | — | CN | disclosed |
| US-20160311804-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2016-10-27 | — | — | US | disclosed |
| US-20160311804-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2016-10-27 | — | — | US | disclosed |
| US-9346751-B2 | Process for preparing 1, 3-Dihydroimidazole-2-Thione Derivatives | BIAL-PORTELA & CA, S.A. (PT) | 2016-05-24 | — | — | US | disclosed |
| US-9346751-B2 | Process for preparing 1, 3-Dihydroimidazole-2-Thione Derivatives | BIAL-PORTELA & CA, S.A. (PT) | 2016-05-24 | — | — | US | disclosed |
| US-20140221668-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2014-08-07 | — | — | US | disclosed |
| US-20140221668-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2014-08-07 | — | — | US | disclosed |
| US-20070054224-A1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2007-03-08 | — | — | US | disclosed |
| US-20070054224-A1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2007-03-08 | — | — | US | disclosed |
| US-7183044-B2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183044-B2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7175976-B2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-7175976-B2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| EP-1321454-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | Kaneka Corporation (JP) | 2003-06-25 | — | — | EP | disclosed |
| US-6515179-B2 | Reacting nitrobenzenesulfonyl group containing compound contacting with alkali metal alkoxide | KANEKA CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20030009056-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | KANEKA CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221668-A1 | Process | DHPS, CYP3A5, SULT1E1 | CYP19A1 1717/4885LMNA 4254/4885ALDH1A1 336/4885 |
| US-20160311804-A1 | Process | DHPS, CYP3A5, SULT1E1 | CYP19A1 1717/4885LMNA 4254/4885ALDH1A1 336/4885 |
| US-20030009056-A1 | PROCESS FOR THE REMOVAL OF NITROBENZENESULFONYL | NAAA, TST, AADAC | CYP19A1 1518/4885LMNA 4195/4885ALDH1A1 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.