Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989679 | 0.84 | PKM (0.57) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL8560755 | 0.79 | PKM (0.57) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL9539135 | 0.76 | NPC1 (0.74) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL9304632 | 0.75 | NPC1 (0.56) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL4034758 | 0.74 | NPC1 (0.62) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL9685901 | 0.74 | PKM (0.57) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL5119326 | 0.73 | PDE10A (0.60) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL31631301 | 0.73 | NPC1 (0.74) | PKMNPC1RAB9AMAPTLMNA | |
| SCHEMBL1738419 | 0.73 | NPC1 (0.74) | PKMNPC1RAB9AMAPTLMNA | |
| Methyl Alcohol SCHEMBL10640492 | 0.73 | NPC1 (0.70) | PKMNPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043640-C | Oxazolyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1999-06-16 | — | — | CN | disclosed |
| EP-0539421-B1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1998-09-23 | — | — | EP | disclosed |
| US-5278165-A | Oxazolyl imidazol[4,5-b]pyridin and pyrimidine compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-01-11 | — | — | US | disclosed |
| US-5217980-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-06-08 | — | — | US | disclosed |
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |
| CN-1058215-A | Novel oxazolyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1992-01-29 | — | — | CN | disclosed |