Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173122 | 0.95 | EPHX2 (0.49) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL6763238 | 0.92 | EPHX2 (0.51) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6758607 | 0.91 | EPHX2 (0.46) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17754031 | 0.89 | ACHE (0.45) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL8558896 | 0.87 | EPHX2 (0.46) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17753923 | 0.87 | ACHE (0.42) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL4099875 | 0.85 | CYP1A2 (0.52) | EPHX2 | |
| SCHEMBL21821530 | 0.84 | HTR2C (0.54) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL4100220 | 0.84 | EPHX2 (0.51) | EPHX2DGKA | |
| Trifluoroacetic Acid SCHEMBL6758189 | 0.83 | EPHX2 (0.44) | EPHX2DGKAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |