Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6758189 | 0.94 | EPHX2 (0.44) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL8560286 | 0.91 | EPHX2 (0.52) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL8173122 | 0.86 | EPHX2 (0.49) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL6763238 | 0.83 | EPHX2 (0.51) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17753923 | 0.82 | ACHE (0.42) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17754031 | 0.81 | ACHE (0.45) | EPHX2DGKAPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL20542873 | 0.80 | CASP2 (0.53) | EPHX2S1PR1S1PR3S1PR2S1PR5 | |
| Trifluoroacetic Acid SCHEMBL20542984 | 0.80 | CASP2 (0.53) | EPHX2S1PR1S1PR3S1PR2S1PR5 | |
| Trifluoroacetic Acid SCHEMBL6759516 | 0.79 | EPHX2 (0.43) | EPHX2S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL8558896 | 0.79 | EPHX2 (0.46) | EPHX2DGKAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759420-B1 | LOW MOLECULAR WEIGHT, FACTOR XA SPECIFIC BLOOD CLOTTING INHIBITORS WITHOUT SIDE EFFECTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-06 | — | — | US | disclosed |