Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567052 | 0.92 | MAPT (0.55) | MAPTNPC1SMN1; SMN2PAX8 | |
| Hydrochloric Acid SCHEMBL8566227 | 0.91 | MAPT (0.54) | MAPTNPC1SMN1; SMN2PAX8 | |
| SCHEMBL8564146 | 0.89 | CSF1R (0.50) | MAPTNPC1SMN1; SMN2PAX8CSF1R | |
| SCHEMBL8330039 | 0.88 | MAPT (0.44) | MAPTNPC1SMN1; SMN2KDM4EPAX8 | |
| SCHEMBL8567066 | 0.85 | MAPT (0.40) | MAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL8559604 | 0.84 | MAPT (0.62) | MAPTNPC1SMN1; SMN2KDM4EPAX8 | |
| Hydrochloric Acid SCHEMBL8561142 | 0.83 | MAPT (0.61) | MAPTNPC1SMN1; SMN2KDM4EPAX8 | |
| SCHEMBL8328843 | 0.83 | MEN1 (0.42) | MAPTNPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8329674 | 0.83 | MAPT (0.43) | MAPTNPC1SMN1; SMN2KDM4E | |
| SCHEMBL8326891 | 0.82 | MAPT (0.55) | MAPTNPC1SMN1; SMN2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | claimed |