Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562498 | 0.90 | STK4 (0.45) | MAPTNPC1KDM4ELMNASTK4 | |
| SCHEMBL8567052 | 0.86 | MAPT (0.55) | MAPTNPC1LMNATP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8566227 | 0.85 | MAPT (0.54) | MAPTNPC1LMNATP53SMN1; SMN2 | |
| SCHEMBL8560369 | 0.85 | MAPT (0.44) | MAPTNPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8559604 | 0.79 | MAPT (0.62) | MAPTNPC1KDM4ETP53KMT2A | |
| Hydrochloric Acid SCHEMBL8561142 | 0.78 | MAPT (0.61) | MAPTNPC1KDM4ETP53KMT2A | |
| SCHEMBL8567858 | 0.76 | MAPT (0.51) | MAPTNPC1LMNATP53SMN1; SMN2 | |
| SCHEMBL8566689 | 0.76 | PDE4B (0.43) | MAPTNPC1KDM4ESTK4TP53 | |
| SCHEMBL8563378 | 0.76 | PDE4B (0.59) | MAPTNPC1TP53KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL8562082 | 0.76 | MAPT (0.51) | MAPTNPC1LMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | claimed |