Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597281 | 0.85 | SMN1; SMN2 (0.47) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL25257796 | 0.84 | NPC1 (0.42) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL9327435 | 0.83 | MAPT (0.49) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL29179660 | 0.83 | HTT (0.45) | ALDH1A1MAPTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL8564571 | 0.79 | MAPT (0.43) | ALDH1A1MAPTRAB9ALMNAHTT | |
| SCHEMBL31327471 | 0.79 | LMNA (0.51) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL11596026 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL26087355 | 0.78 | CHEK1 (0.43) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL5512119 | 0.78 | RECQL (0.50) | ALDH1A1MAPTNPC1RAB9ARECQL | |
| SCHEMBL22072961 | 0.77 | MAPT (0.56) | ALDH1A1MAPTNPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |