SCHEMBL8560469

SCHEMBL8560469

Oc1ccccc1Oc1ccc(-c2ccc(Oc3ccccc3O)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.48
CA1 P00915 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
AR P10275 1/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
JAK2 O60674 1/20 0.45
GAA P10253 1/20 0.45
TTR P02766 2/20 0.44
LTA4H P09960 1/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
IKBKB O14920 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29833728 1.00 CA2 (0.48) CA2CA1TP53TSHRALDH1A1
SCHEMBL29024081 0.93 CA2 (0.54) CA2CA1TP53TSHRALDH1A1
SCHEMBL9344917 0.91 TSHR (0.52) CA2CA1TP53TSHRALDH1A1
Biphenyl SCHEMBL28813894 0.89 TTR (0.52) CA2CA1TP53TSHRALDH1A1
SCHEMBL10536978 0.87 SRD5A2 (0.51) CA2CA1L3MBTL1LMNAMAPT
SCHEMBL5528855 0.86 LTA4H (0.60) CA2CA1TP53TSHRALDH1A1
SCHEMBL68185 0.86 LTA4H (0.60) CA2CA1TP53TSHRALDH1A1
SCHEMBL260447 0.86 TTR (0.57) CA2CA1TP53TSHRALDH1A1
SCHEMBL29449754 0.86 TTR (0.57) CA2CA1TP53TSHRALDH1A1
SCHEMBL9804483 0.86 CYP11B1 (0.53) CA2CA1MAPK1ARLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379058-B1 Vinyl ester resins containing mesogenic/rigid rodlike moieties DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5164464-A Liquid crystalline polymers, acrylated epoxy resins THE DOW CHEMICAL COMPANY (US) 1992-11-17 US claimed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US claimed
EP-0379058-A2 Vinyl ester resins containing mesogenic/rigid rodlike moieties THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed
EP-0379058-B1 Vinyl ester resins containing mesogenic/rigid rodlike moieties DOW CHEMICAL CO (US) 1999-09-29 EP disclosed
EP-0708796-B1 PROCESS FOR PREPARING COMPOSITES BASED ON ORIENTED MESOGENIC THERMOSET RESINS DOW CHEMICAL CO (US) 1998-05-27 EP disclosed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US disclosed
US-5464912-A Adduct with rodlike mesogenic moiety, adduct made by reacting polyepoxide with nitro/so/ compound having epoxy-reactive hydrogen; conversion of hydroxyl product to ether, ester, halide, urethane, ketone, alkane; reducing nitro/so/ to amine THE DOW CHEMICAL COMPANY (US) 1995-11-07 US disclosed
US-5424393-A Curing into liquid crystals THE DOW CHEMICAL COMPANY (US) 1995-06-13 US disclosed
US-5418271-A Mixed metal hydroxide colloidal dispersion THE DOW CHEMICAL COMPANY (US) 1995-05-23 US disclosed
WO-1985001943-A1 PROCESSES FOR PREPARING HYDROXYAROMATIC OLIGOMERS CONTAINING TRIAZINE GROUPS AND FOR PREPARING EPOXY RESINS FROM THE OLIGOMERS THE DOW CHEMICAL COMPANY (US) 1985-05-09 WO disclosed
US-4515934-A COATINGS, CASTINGS THE DOW CHEMICAL COMPANY (US) 1985-05-07 US disclosed
US-4506063-A HEAT RESISTANCE; ELONGATION THE DOW CHEMICAL COMPANY (US) 1985-03-19 US disclosed
US-4489202-A TRIMERIZATION OF A CYANATED DIHYDRIC CARBOALCOHOL; HEAT RESISTANT CASTINGS THE DOW CHEMICAL COMPANY (US) 1984-12-18 US disclosed
US-4487915-A CASTINGS, COATINGS, LAMINATION THE DOW CHEMICAL COMPANY (US) 1984-12-11 US disclosed
US-4094861-A Process for the production of non-inflammable polytriazines BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-3978028-A Process for preparing s-triazine prepolymers by condensation of an aromatic polyhydroxy compound with cyanuric chloride and thereafter reacting the condensation product with cyanogen halide in the presence of base BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed