Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 3/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556252 | 0.89 | NAMPT (0.63) | HPGDNAMPTALDH1A1NPC1RAB9A | |
| SCHEMBL8561097 | 0.88 | AVPR2 (0.52) | NAMPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8562633 | 0.85 | AVPR2 (0.55) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8557607 | 0.83 | NPC1 (0.50) | ALDH1A1NPC1RAB9A | |
| SCHEMBL8563072 | 0.83 | SMN1; SMN2 (0.55) | NAMPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8563565 | 0.82 | NAMPT (0.50) | NAMPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8558377 | 0.82 | NAMPT (0.54) | NAMPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8560580 | 0.81 | AVPR2 (0.56) | ALDH1A1 | |
| SCHEMBL8555952 | 0.80 | NAMPT (0.51) | HPGDNAMPTALDH1A1NPC1RAB9A | |
| SCHEMBL8562097 | 0.80 | AVPR2 (0.49) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |